Publications

Profiling the genomic landscape and evolutionary history of polyploid giant cancer cells in undifferentiated pleomorphic sarcomas - Bowes AL, Waise S, Lesluyes T, Butters T, English C, Yan H, Verfaillie A, Chen J, Davies C, Nye E, Stone R, Manji J, Flanagan AM, Demeulemeester J, Tarabichi M, Pillay N, Van Loo P - 2026 - Cancer Letters - Pubmed 

Optical Genome Mapping Is a Powerful Diagnostic Tool in Non-Hodgkin Lymphoma - Verhasselt A, Vanhevel J, Tousseyn T, Vets J, Hauben E, Meeus P, Vanden Bempt M, Debackere K, Forsyth RA, Harbers L, Demeulemeester J, Michaux L, Rack K, Dewaele B, De Bie J - 2026 - Modern Pathology - Pubmed

Emerging insights into mosaic errors of immunity - Roosens W, Demeulemeester J, Legius E, Savic S, Schrijvers R - 2026 - Trends in Immunology - Pubmed 

Single-cell genome and transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones - Theunis S., Vanuytven S., Claes I., Geurts J., Rambow F., Brown D., Van Der Haegen M., Marin-Bejar O., Rogiers A., Van Raemdonck N., Leucci E., Demeulemeester J., Sifrim A., Marine J-C., Voet T. - 2025 - Nucleic Acids Research - PubMed 

DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution - Gimeno-Valiente F., Castignani C., Larose Cadieux E., Mensah NE., Liu X., Chen K., Chervova O., Karasaki T., Weeden CE., Richard C., Lai S., Martínez-Ruiz C., Lim E., Frankell AM., Watkins TBK., Stavrou G., Usaite I., Lu W-T., Marinelli D., Saghafinia S., Wilson GA., Dhami P., Vaikkinen H., Steif J., Veeriah S., Hynds RE., Hirst M., Hiley C., Feber A., Deniz Ö., Jamal-Hanjani M., McGranahan N., TRACERx Consortium, Beck S., Demeulemeester J., Tanić M., Swanton C., Van Loo P., Kanu N. - 2025 - Nature Genetics - PubMed 

Emerging insights into mosaic errors of immunity - Roosens W., Demeulemeester J., Legius E., Savic S., Schrijvers R. - 2025 - Trends in Immunology - Pubmed 

Single-cell mapping of alternative splicing linked to checkpoint immunotherapy response - Xiong J., Bricard O., Arijs I., Demeulemeester J., Gu Ch., Thienpont B., Daaboul D., Bassez A., Bechter O., Pozniak J., Vos H., Nevelsteen I., Torfs S., Santos SA., Lan Q., Hou Y., Van oudenhove L., Boons G., Qian J., Aerts S., Smeets A., Marine JC., Lambrechts D. - 2025 - Nucleics Acids Research - Pubmed 

Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data - Idkowiak J., Dehairs J., Schwarzerova J., Olesova D., Truong JXM., Kvasnicka A., Eftychiou M., Cools R., Spotbeen X., Jirasko R., Veseli V., Giampa M., de Laat V., Butler LM., Weckwerth W., Friedecky D., Demeulemeester J., Hron K., Swinnen JV., Holcapek M. - 2025 - Nature communications - Pubmed 

ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer - Richard F., Maetens M., Van Baelen K., Borremans K., Van Cauwenberge J., Zels G., Rousseau E., Geukens T., De Schepper M., Mahdami A., Vanderheyden E., Van Brussel T., Nguyen HL., Pabba A., Leduc S., Izci H., Bachir I., Carette C., Hatse S., Nysen M., Vermeulen P., Boeckx B., Lambrechts D., Biganzoli E., Neven P., Wildiers H., Van Den Bogaert W., Demeulemeester J., Floris G., Desmedt C. - 2025 - Nature communications - Pubmed 

Profiling the genomic landscape and evolutionary history of polyploid giant cancer cells in undifferentiated pleomorphic sarcomas - Bowes A.L., Waise S., Lesluyes T., Butters T., English C., Yan H., Verfaillie A., Davies C., Chen J., Nye E., Stone R., Manji J., Flanagan A.M., Demeulemeester J., Tarabichi M., Pillay N., Van Loo P. - 2025 - Cancer Lett. - Pubmed

Optical Genome Mapping Is a Powerful Diagnostic Tool in Non-Hodgkin Lymphoma - Verhasselt A., Ameye G., Vanhevel J., Tousseyn T., Vets J., Hauben E., Meeus P., Bempt M.V., Debackere K., Forsyth R.A., Harbers L., Demeulemeester J., Michaux L., Rack K., Dewaele B., De Bie J. - 2025 - Mod Pathol. - Pubmed

Focal deletions of a promoter tether activate the IRX3 in T-cell acute leukemia - Rahman, S., Bloye, G., Farah, N., Demeulemeester, J., Costa, J.R., O'Connor, D., Pocock, R., Rapoz-D'Silva, T., Turna, A., Wang, L., Lee, S., Fielding, A.K., Roels, J., Jaksik, R., Dawidowska, M., Van Vlierberghe, P., Hadjur, S., Dawson, M.A., Hughes, J.R., Davies, J.O J., Gutierrez, A., Kelliher, M.A., Van Loo, P., Mansour, M.R. with Rahman, S. (corresp. author), Mansour, M.R. (corresp. author) - 2024 - BLOOD - PubMed

Single-cell somatic copy number variants in brain using different amplification methods and reference genomes - Kalef-Ezra, E., Turan, Z.G., Perez-Rodriguez, D., Bomann, I., Behera, S., Morley, C., Scholz, S.W., Jaunmuktane, Z., Demeulemeester, J., Sedlazeck, F.J., Proukakis, C. with Proukakis, C. (corresp. author) - 2024 - Communications Biology - PubMed

Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction - Salcedo, A., Tarabichi, M., Buchanan, A., Espiritu, S.M G., Zhang, H., Zhu, K., Ou Yang, T-H., Leshchiner, I., Anastassiou, D., Guan, Y., Jang, G.H., Mootor, M.F E., Haase, K., Deshwar, A.G., Zou, W., Umar, I., Dentro, S., Wintersinger, J.A., Chiotti, K., Demeulemeester, J., Jolly, C., Sycza, L., Ko, M., PCAWG Evolution and Heterogeneity Working Group, SMC-Het Participants, Wedge, D.C., Morris, Q.D., Ellrott, K., Van Loo, P., Boutros, P.C. - 2024 - Nature Biotechnology - PubMed

The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma - Pan, X., Abduljabbar, K., Coelho-Lima, J., Grapa, A-I., Zhang, H., Cheung, A.H K., Baena, J., Karasaki, T., Wilson, C.R., Sereno, M., Veeriah, S., Aitken, S.J., Hackshaw, A., Nicholson, A.G., Jamal-Hanjani, M., TRACERx  Consortium, Swanton, C., Yuan, Y., Le Quesne, J., Moore, D.A. with Yuan, Y. (corresp. author), Le Quesne, J. (corresp. author), Moore, D.A. (corresp. author) - 2024 - Nature Cancer - PubMed

Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation - Bravo Gonzalez-Blas, C., Matetovici, I., Hillen, H., Taskiran, I.I., Vandepoel, R., Christiaens, V., Sansores-Garcia, L., Verboven, E., Hulselmans, G., Poovathingal, S., Demeulemeester, J., Psatha, N., Mauduit, D., Halder, G., Aerts, S. with Aerts, S. (corresp. author) - 2024 - Nature Cell Biology - PubMed

The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia - O'Connor, D., Demeulemeester, J., Conde, L., Kirkwood, A., Fung, K., Papaleonidopoulou, F., Bloye, G., Farah, N., Rahman, S., Hancock, J., Bateman, C., Inglott, S., Mee, J., Herrero, J., Van Loo, P., Moorman, A.V., Vora, A., Mansour, M.R. - 2023 - Journal of Clinical Oncology - PubMed

Evolutionary characterization of lung adenocarcinoma morphology in TRACERx - Karasaki, T., Moore, D.A., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Magno, N., Ward, S., Bakir, M.A., Watkins, T.B K., Grigoriadis, K., Huebner, A., Hill, M.S., Frankell, A.M., Abbosh, C., Puttick, C., Zhai, H., Gimeno-Valiente, F., Saghafinia, S., Kanu, N., Dietzen, M., Pich, O., Lim, E.L., Martínez-Ruiz, C., Black, J.R M., Biswas, D., Campbell, B.B., Lee, C., Colliver, E., Enfield, K.S S., Hessey, S., Hiley, C.T., Zaccaria, S., Litchfield, K., Birkbak, N.J., Cadieux, E.L., Demeulemeester, J., Van Loo, P., Adusumilli, P.S., Tan, K.S., Cheema, W., Sanchez-Vega, F., Jones, D.R., Rekhtman, N., Travis, W.D., Hackshaw, A., Marafioti, T., Salgado, R., Le Quesne, J., Nicholson, A.G., TRACERx Consortium, , McGranahan, N., Swanton, C., Jamal-Hanjani, M. 2023 - Nature Medicine - PubMed

Genomic-transcriptomic evolution in lung cancer and metastasis. Martínez-Ruiz, C., Black, J.R M., Puttick, C., Hill, M.S., Demeulemeester, J., Larose Cadieux, E., Thol, K., Jones, T.P., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Prymas, P., Rowan, A., Ward, S., Cubitt, L., Athanasopoulou, F., Pich, O., Karasaki, T., Moore, D.A., Salgado, R., Colliver, E., Castignani, C., Dietzen, M., Huebner, A., Al Bakir, M., Tanić, M., Watkins, T.B K., Lim, E.L., Al-Rashed, A.M., Lang, D., Clements, J., Cook, D.E., Rosenthal, R., Wilson, G.A., Frankell, A.M., de Carné Trécesson, S., East, P., Kanu, N., Litchfield, K., Birkbak, N.J., Hackshaw, A., Beck, S., Van Loo, P., Jamal-Hanjani, M., TRACERx Consortium, , Swanton, C., McGranahan, N. – 2023 – Nature - PubMed

Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression - Cao S, Wang JR, Ji S, Yang P, Dai Y, Guo S, Montierth MD, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Viale A, Zhang J, Nykter M, Czerniak BA, Brown PH, Swanton C, Msaouel P, Maitra A, Kopetz S, Campbell P, Speed TP, Boutros PC, Zhu H, Urbanucci A, Demeulemeester J, Van Loo P, Wang W. - 2022 - Nature Biotechnology - PubMed

Primary mediastinal large B-cell lymphoma is characterized by large-scale copy-neutral loss of heterozygosity - Tuveri S, Debackere K, Marcelis L, Dierckxsens N, Demeulemeester J, Dimitriadou E, Dierickx D, Lefesvre P, Deraedt K, Graux C, Michaux L, Cools J, Tousseyn T, Vermeesch JR, Wlodarska I. - 2022 - Genes Chromosomes Cancer - PubMed

A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer - Wu Y, Biswas D, Usaite I, Angelova M, Boeing S, Karasaki T, Veeriah S, Czyzewska-Khan J, Morton C, Joseph M, Hessey S, Reading J, Georgiou A, Al-Bakir M; TRACERx Consortium, McGranahan N, Jamal-Hanjani M, Hackshaw A, Quezada SA, Hayday AC, Swanton C. - 2022 - Nature Cancer - PubMed

Biallelic mutations in cancer genomes reveal local mutational determinants - Demeulemeester J.#, Dentro S.C., Gerstung M., Van Loo P.# - 2022 - Nature Genetics - PubMed

Analysis of long and short enhancers in melanoma cell states - Mauduit D., Taskiran I.I., Minnoye L., de Waegeneer M., Christiaens V., Hulselmans G., Demeulemeester J., Wouters J., Aerts S. - 2021 - ELIFE - PubMed

A ubiquitous disordered protein interaction module orchestrates transcription elongation - Cermakova K*, Demeulemeester J.*, Lux V.*, Siva, M., Goldman, S.R., Smith E.A., Srb P., Hexnerova R., Fabry M., Madlikova M., Horejsi M., De Rijck J., Debyser Z., Adelman, K., Hodges H.C.#, Veverka V.# - 2021 - Science - PubMed

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture - Álvarez E.G., Demeulemeester J.*, Jolly C.*, García-Souto D.*, Otero P.*, Pequeño A., Zamora J., Tojo M., Temes J., Baez-Ortega A., Rodríguez-Martín B., Li Y., Oitaben A., Bruzos A.L., Martínez-Fernandez M., Haase K., Santamarina M., Zumalave S., Abal R., Rodríguez-Castro J., Raine K., Butler A.P., Ono A., Aikata H., Chayama K., Ueno M., Hayami S., Yamaue H., Blanco M.G., Forns X., Rivas C., Perez del Pulgar S., Torres R., Perales S.R., Garaigorta U.#, Nakagawa H.#, Campbell P.J.#, Van Loo P.#, Tubio J.M.C. - 2021 - Nature Communications - PubMed

Using DNA sequencing data to quantify T cell fraction and therapy response - Bentham R., Litchfield K., Watkins T.B.K., Lim E.L., Rosenthal R., Martínez-Ruiz C., Hiley C.T., Al Bakir M., Salgado R., Moore D.A., Jamal-Hanjani M., TRACERx Consortium, Swanton C., McGranahan N. - 2021 - Nature - PubMed

A pan-cancer landscape of somatic substitutions in non-unique regions of the human genome - Tarabichi M., Demeulemeester J., Verfaillie A., Flanagan AM, Van Loo P., Konopka T. - 2021 - Nature Biotechnology - PubMed

Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma - Marin-Bejar O., Rogiers A., Dewaele M., Femel J., Karras P., Pozniak J., Bervoets G., Van Raemdonck N., Pedri D., Swings T., Demeulemeester J., Vander Borght S., Lehnert S., Bosisio S., van den Oord J.J., Vanden Bempt I., Lambrechts D, Voet T., Bechter O., Rizos, H., Levesque M.P., Leucci E., Lund AW., Rambow F.#, Marine J-C.# - 2021 - Cancer Cell - PubMed

Interpretation of allele-specific chromatin accessibility using cell state-aware deep learning - Kalender-Atak Z.*, Taskiran I.I.*, Demeulemeester J., Flerin C., Mauduit D., Minnoye L., Hulselmans G., Christiaens V., Ghanem G-E., Wouters J., Aerts S. - 2021 - Genome Research - PubMed

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes - Dentro S.*, Leshchiner I.*, Haase K.*, Tarabichi M.*, Wintersinger J.*, Deshwar A.*, Yu K.*, Rubanova Y.*, Macintyre G.*, Demeulemeester J.*, Vasquez-García I., Kleinhenz K., Livitz DG., Malikic S., Donmez N., Sengupta S., Anur P., Jolly C., Cmero M, Rosebrock D., Schumacher S., Fan Y., Fittall MW., Drews RM., Yao X., Lee J., Schlesner M., Zhu H., Adams D., Getz G., Boutros PC., Imielinski M., Beroukhim R., Sahinalp SC., Ji Y., Peifer M., Martincorena I., Markowetz F., Mustonen V., Yuan K,. Gerstung M., Spellman PT., Wang W.#, Morris Q.#, Wedge DC.#, Van Loo P.#, the PCAWG Evolution and Heterogeneity Working Group, and the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network - 2021 - CELL - PubMed

Transcriptional Profiling of STAT1 Gain-of-Function Reveals Common and Mutation-Specific Fingerprints - Giovannozzi S., Demeulemeester J., Schrijvers R., Gijsbers R. - 2021 - Frontiers in Immunology - PubMed

Drivers underpinning the malignant transformation of giant cell tumour of bone - Fittall M.W., Lyskjaer I., Ellery P., Lombard P., Ijaz J., Strobl A-C., Oukrif D., Tarabichi M., Sill M., Koelsche C., Mechtersheimer G., Demeulemeester J., Tirabosco R., Amary F., Campbell P.J., Pfister S., Jones D.T W., Pillay N., Van Loo P., Behjati S.#, Flanagan A.M.# - 2020 - Journal of Pathology - PubMed

Pervasive Chromosomal Instability and Karyotype Order During Tumour Evolution - Watkins T. B. K.*, Li, E. L.*, Petkovic M., Elizalde S., Birkbak N. J., Wilson G.A., Moore D.A., Grönroos, E., Rowan A., Dewhurst S.M., Demeulemeester J., Dentro S.C., Horswell S., Au L., Haase K., Escudero M., Rosenthal R., Al Bakir M., Xu H., Litchfield K., Ting Lu W., Mourikis T.P., Dietzen M., Spain L., Cresswell G.D., Biswas D., Lamy P., Nordentoft I., Harbst K., Castro-Giner F., Yates L. R., Caramia F., Jaulin F., Vicier C., Tomlinson I.P.M., Brastianos P.K., Cho, R.J., Bastian B.C., Dyrskjøt L., Jönsson, G.B., Savas P., Loi S., Campbell P.J., Andre F., Luscombe N.M., Steeghs N., Tjan–Heijnen V.C.G., Szallasi Z., Turajlic S., Jamal-Hanjani M., Van Loo P., Bakhoum S.F., Schwarz R.F.#, McGranahan N.#, Swanton, C.# - 2020 - Nature - PubMed

Sex differences in oncogenic mutational processes - Li C.H., Prokopec S.D., Sun R.X., Yousif F., Schmitz N., PCAWG Tumour Subtypes and Clinical Translation, Boutros P.C., PCAWG Consortium - 2020 - Nature Communications - PubMed

Pan-cancer analysis of whole genomes - The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network - 2020 - Nature - PubMed
(shared first author on 3 out of 8 scientific vignettes with structured author list)

The evolutionary history of 2,658 cancers - Gerstung M.*, Jolly C.*, Leshchiner I.*, Dentro SC.*, Gonzalez S.*, Rosebrock D., Mitchell TJ., Rubanova Y., Anur P., Yu K., Tarabichi M., Deshwar A., Wintersinger J., Kleinheinz K., Vázquez-García I., Haase K., Jerman L., Sengupta S., Macintyre G., Malikic S., Donmez N., Livitz DG., Cmero M., Demeulemeester J., Schumacher S., Fan Y., Yao X., Lee J., Schlesner M., Boutros PC., Bowtell DB., Zhu H., Getz G., Imielinski M., Beroukhim R., Sahinalp SC., Ji Y., Peifer M., Markowetz F., Mustonen V., Yuan K., Wang W., Morris Q., Spellman PT.#, Wedge DC.#, Van Loo P.#, the PCAWG Evolution and Heterogeneity Working Group, and the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network - 2020 - Nature - Pubmed

Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig - Rubanova Y., Shi R., Harrigan C.F., Li R., Wintersinger J., Sahin N., Deshwar A., PCAWG Evolution and Heterogeneity Working Group, Morris Q., PCAWG Consortium - 2020 - Nature Communications - PubMed

Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours - Rodriguez-Martin B., Alvarez E.*, Baez-Ortega A.*, Zamora J.*, Supek F.*, Demeulemeester J., Santamarina M., Ju YS., Temes J., Garcia-Souto D., Detering H., Li Y., Rodriguez-Castro J., Dueso-Barroso A., Bruzos A., Dentro SC., Blanco M., Contino G., Ardeljan D., Tojo M., Roberts ND., Zumalave S., Edwards, P., Weischenfeldt J., Puiggros M., Chong Z., Chen K., Lee E.A., Wala J., Raine K., Butler A., Waszak S., Navarro F., Schumacher S., Monlong J., Maura F., Bolli N., Bourque G., Gerstein M., Park P., Wedge DC., Beroukhim R., Torrents D., Korbel JO., Martincorena I., Fitzgerald R., Van Loo P., Kazazian H., Burns, K, Campbell PJ.#, Tubio J.#, the PCAWG Structural Variation Working group, and the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network - 2020 - Nature Genetics - PubMed

Inferring structural variant cancer cell fraction - Cmero M., Yuan K., Ong C.S., Schröder J. PCAWG Evolution and Heterogeneity Working Group, Corcoran N.M., Papenfuss T., Hovens C.M., Markowetz F., Macintyre G., PCAWG Consortium - 2020 - Nature Communications - PubMed

Butler enables rapid cloud-based analysis of thousands of human genomes - Yakneen S., Waszak S.M., PCAWG Technical Working Group, Gertz M., Korbel J.O., PCAWG Consortium - 2020 - Nature Biotechnology - PubMed

Neoantigen-directed immune escape in lung cancer evolution - Rosenthal R., Larose-Cadieux E.*, Salgado R.*, Al Bakir M.*, Moore DA.*, Hiley CT., Lund T.*, Tanic M., Reading JL., Joshi K., Henry JY., Ghorani E., Wilson GA., Birkbak NJ., Jamal-Hanjani M., Veeriah S., Szallasi Z., Loi S., Hellmann MD., Feber A., Chain B., Herrero J., Quezada SA., Demeulemeester J., Van Loo P., Beck S., McGranahan N.#, Swanton C.#, the TRACERx consortium - 2019 - Nature - PubMed

Neutral tumor evolution?  - Tarabichi M., Martincorena I., Gerstung M., Leroi AM., The PCAWG Evolution and Heterogeneity Working Group, Markowetz F., Spellman PT., Morris QD., Lingjaerde OC., Wedge DC., Van Loo P. - 2018 - Nature Genetics - PubMed

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation - Sharma S.*, Cermakova K.*, De Rijck J.*, Demeulemeester J., Fabry M., El Ashkar S., Van Belle S., Lepsik M., Tesina P., Duchoslav V., Novak P., Hubalek M., Srb P., Christ F., Rezacova P., Hodges HC., Debyser Z., Veverka V. - 2018 - Proc Nat Acad Sciences N Am - PubMed

Recurrent rearrangements of FOS and FOSB define osteoblastoma - Fittall MW.*, Mifsud W.*, Pillay N., Ye H., Strobl A-C., Verfaillie A., Demeulemeester J., Zhang L., Berisha F., Tarabichi M., Young MD., Miranda E., Tarpey PS., Tirabosco R., Amary F., Grigoriadis AE., Stratton MR., Van Loo P., Antonescu CR., Campbell PJ., Flanagan AM., Behjati S. - 2018 - Nature Communications - PubMed

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis - El Ashkar S., Schwaller J., Pieters T., Goossens S., Demeulemeester J., Christ F., Van Belle S., Juge S., Boeckx N., Engelman A., Van Vlierberghe P., Debyser Z., De Rijck J. - 2018 - BLOOD - PubMed

Inhibitors of the integrase-transportin-SR2 interaction block HIV nuclear import - Demeulemeester J.*, Blokken J.*, De Houwer S., Dirix L., Klaassen H., Marchand A., Chaltin P., Christ F., Debyser Z. - 2018 - Retrovirology - PubMed

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy - El Ashkar S., Van Looveren D., Schenk F., Vranckx LS., Demeulemeester J., De Rijck J., Debyser Z., Modlich U., Gijsbers R. - 2017 - Molecular Therapy-Nucleic Acids - PubMed

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors - Cheng J.*, Demeulemeester J.*, Wedge DC., Vollan HK M., Pitt JJ., Russnes HG., Pandey BP., Nilsen G., Nord S., Bignell GR., White KP., Borresen-Dale A-L., Campbell PJ., Kristensen VN., Stratton MR., Lingjrde OC., Moreau Y., Van Loo P. - 2017 - Nature Communications - PubMed

LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV - Vranckx LS., Demeulemeester J., Saleh S., Boll A., Vansant G., Schrijvers R., Weydert C., Battivelli E., Verdin E., Cereseto A., Christ F., Gijsbers R., Debyser Z. - 2016 - EBiomedicine - PubMed

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing - Demeulemeester J.*, Kumar P.*, Moller EK.*, Nord S., Wedge DC., Peterson A., Mathiesen RR., Fjelldal R., Esteki MZ., Theunis K., Gallardo EF., Grundstad AJ., Borgen E., Baumbusch LO., Borresen-Dale A-L., White KP., Kristensen VN., Van Loo P., Voet T., Naume B. - 2016 - Genome Biology - PubMed

Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras - Vranckx LS., Demeulemeester J., Debyser Z., Gijsbers R. - 2016 - PLOS ONE - PubMed